GLP-1 also known as Liraglutide is a naturally occurring peptide that is known to stimulate insulin secretion. Research shows that it may potentially lower blood sugar levels and improve heart, liver, and lung function, making it a popular choice for researchers to combine with MK 677 which can potentially increase blood sugar levels.
The peptide has also been shown to potentially slow or prevent the effects of Alzheimer’s disease.
GLP-1 has also been found to potentially improve cardiac muscle glucose uptake. In addition, research has shown that it may possesses anti-diabetic and anti-obesity effects. Pure Rawz sells Liraglutide, a synthetic derivative of GLP-1, for medical research purposes only.
Liraglutide, also known as Victoza and Saxenda, is an agonist of glucagon-like peptide 1 (GLP-1). It has been shown to potentially inhibit beta cell apoptosis and enhance beta cell growth in vitro. Liraglutide has also been shown to potentially slow gastric emptying to encourage weight loss.
Liraglutide was developed by substituting arginine for lysine at position 34 in the GLP-1 peptide. It was developed because GLP-1 has a poor pharmacokinetic profile. The peptide has a half-life of only 2 minutes and is rapidly degraded by the actions of natural enzymes.
In healthy individuals and those with type 2 diabetes, Liraglutide has exhibited a potential half-life of 13 hours. Research has shown that its absolute bioavailability (the proportion which produces an active effect) is 55%. Gastrointestinal side effects may potentially occur.
Since November 2010, Liraglutide has been an approved treatment for type 2 diabetes. The US Food and Drug Administration (FDA) has also approved it for chronic weight management in obese patients. Pure Rawz does not sell Liraglutide for human consumption.