Ibutamoren (MK-677)


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MK 677 or Ibutamoren is an anabolic research compound being investigated in current animal studies that showed promising results to the potential of effectively increasing lean body mass in an aim to grow muscle. Due to the potential ability to increase growth hormone levels, the research aims have shifted towards proving MK 677 supplementation as a means of elevating muscle mass, muscle strength, and reducing overall body fat.

Studies indicate that MK-677 compounds may spur the growth of new muscle cells by signaling the pituitary gland to create more growth hormones and by stimulating IGF 1 release in the liver. According to studies, these hormones together may increase protein synthesis and strength while simultaneously boosting recovery rate and enhancing nitrogen retention.

In a double-blind randomized controlled trial, 24 obese mice received MK 677 therapy for two months. Results showed their basal metabolic rates and muscle mass increased. Another study on mice found that MK 677 effects reversed muscle wasting and muscle loss. Meanwhile, another study carried out on mice suffering hip fractures found evidence of improved muscle strength when administering a MK 677 cycle.

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