RAD 140 (Testolone)


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RAD 140, also known as Testolone, is a non-steroidal selective androgen receptor modulator (SARM). Like other SARMs, it binds to specific androgen receptors and doesn’t cause the full spectrum of androgenic effects as similar substances like anabolic steroids, DHT, or testosterone replacement therapy.

Testolone hasn’t been around for long. This research compound was developed in 2010 as a potential treatment for osteoporosis. At the time of writing, it is being investigated as a research compound for its potential ability to enhance muscle hypertrophy and promote muscular gains.

Research has shown that the stability of RAD-140 is high in incubations with rats, monkeys, and human microsomes. The research compound has also demonstrated good bioavailability in rats and monkeys as well as excellent affinity for the androgen receptor in the skeletal tissue.

Recent studies investigated the effects of RAD-140 on levator ani muscle weight and prostate weight in castrated rats, which are sensitive markers of anabolic-androgenic action in young nonhuman primates. The final results showed that RAD-140 stimulates the levator ani muscle.

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