Description
GW–501516 of interest for 2 reasons. Firstly, it seems to have a dose–dependent effect on HDL–cholesterol and, second, because it could have an indirect effect on endogenous androgens. GW–501516 is a PPAR–delta agonist, which has been shown to favorably impact HDL–cholesterol levels. This is possibly through a down–regulation of the catabolism of apo A–I and apo A–II. Secondly, this PPAR–delta agonist also seemed to have a favorable effect on endogenous androgens. This is because it has been shown to inhibit the expression of the enzyme 3β–HSD, which is responsible for the conversion of testosterone to dihydrotestosterone.
Cardarine | |
CAS Number | 317318-70-0 |
Molar Mass | 453.49 g·mol−1 |
Chemical Formula | C21H18F3NO3S2 |
IUPAC Name | {4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid |
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