Description
GW–501516 of interest for 2 reasons. Firstly, it seems to have a dose–dependent effect on HDL–cholesterol and, second, because it could have an indirect effect on endogenous androgens. GW–501516 is a PPAR–delta agonist, which has been shown to favorably impact HDL–cholesterol levels. This is possibly through a down–regulation of the catabolism of apo A–I and apo A–II. Secondly, this PPAR–delta agonist also seemed to have a favorable effect on endogenous androgens. This is because it has been shown to inhibit the expression of the enzyme 3β–HSD, which is responsible for the conversion of testosterone to dihydrotestosterone.
| Cardarine | |
| CAS Number | 317318-70-0 |
| Molar Mass | 453.49 g·mol−1 |
| Chemical Formula | C21H18F3NO3S2 |
| IUPAC Name | {4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid |





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