Description
Ligandrol is a novel nonsteroidal oral selective androgen receptor modulator currently being investigated in research as a potential treatment for conditions relating to muscle dystrophy and osteoporosis. A recent study has shown that YK11, a selective androgen receptor myostatin inhibitor, accelerates the expression of follistatin in mice.
Follistatin is a myostatin and activin-binding protein naturally found in the human body and has been used as a treatment for several degenerative muscle diseases. When follistatin levels are raised, myostatin levels will be inhibited. Inhibition of myostatin results in increased muscle mass and improved strength.
| LGD-4033 | |
| CAS Number | 1165910-22-4 |
| Molar Mass | 338.253 g·mol−1 |
| Chemical Formula | C14H12F6N2O |
| IUPAC Name | 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile |
| YK-11 | |
| CAS Number | 1370003-76-1 |
| Molar Mass | 430.541 g·mol−1 |
| Chemical Formula | C25H34O6 |
| IUPAC Name | methyl (2E)-2-[(8R,9S,10R,13S,14S,17S)-2′-methoxy-2′,13-dimethyl-3-oxospiro[1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-17,5′-1,3-dioxolane]-4′-ylidene]acetate |
| S23 | |
| CAS Number | 1010396-29-8 |
| Molar Mass | 416.76 g·mol−1 |
| Chemical Formula | C18H13ClF4N2O3 |
| IUPAC Name | (2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide |
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