Description

Testolone, also known as RAD 140, is being investigated as a potential treatment for conditions relating to muscle dystrophy and osteoporosis. A study found that rats which received a daily dose of LGD 4033 weighed significantly more than the control group, and that the LGD treatments resulted in a higher number of capillaries in all muscles studied. Longer randomized trials and research could potentially evaluate its efficacy in improving physical function and health outcomes in select populations.

LGD-4033
CAS Number	1165910-22-4
Molar Mass	338.253 g·mol−1
Chemical Formula	C14H12F6N2O
IUPAC Name	4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile

RAD-140
CAS Number	1182367-47-0
Molar Mass	393.83 g·mol−1
Chemical Formula	C20H16ClN5O2
IUPAC Name	2-chloro-4-{[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino}-3-methylbenzonitrile

S23
CAS Number	1010396-29-8
Molar Mass	416.76 g·mol−1
Chemical Formula	C18H13ClF4N2O3
IUPAC Name	(2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide