Description
GW0742 is a PPARβ/δ agonist that has been shown to improve glucose homeostasis and insulin sensitivity in diabetic rats, as well as increase fat loss. Treatment with GW0742 has also been shown to improve dyslipidemia and hyperglycemia in diet-induced obese mice. The activation of PPARβ/δ by GW0742 leads to enhanced circadian rhythm, which affects behaviour, sleep cycle and some functions related to increment in energy production.
GW0742 |
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CAS Number |
317318-84-6 |
Molar Mass |
471.48g.mol-1 |
Chemical Formula |
C21H17F4NO3S2 |
IUPAC Name |
2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid |
SR9011 |
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CAS Number |
1379686-29-9 |
Molar Mass |
479.04 g·mol−1 |
Chemical Formula |
C23H31ClN4O3S |
IUPAC Name |
3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide |
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