Description

Ligandrol is a novel nonsteroidal oral selective androgen receptor modulator (SARM) currently being investigated in research as a potential treatment for conditions relating to muscle dystrophy and osteoporosis. A recent study has shown that YK11, a selective androgen receptor myostatin inhibitor, accelerates the expression of Follistatin in mice. Follistatin is a myostatin and activin-binding protein naturally found in the human body and has been used as a treatment for several degenerative muscle diseases. When follistatin levels are raised, myostatin levels will be inhibited. Inhibition of myostatin results in increased muscle mass and improved strength.

LGD-4033
CAS Number	1165910-22-4
Molar Mass	338.253 g·mol−1
Chemical Formula	C14H12F6N2O
IUPAC Name	4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile

YK-11
CAS Number	1370003-76-1
Molar Mass	430.541 g·mol−1
Chemical Formula	C25H34O6
IUPAC Name	methyl (2E)-2-[(8R,9S,10R,13S,14S,17S)-2′-methoxy-2′,13-dimethyl-3-oxospiro[1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-17,5′-1,3-dioxolane]-4′-ylidene]acetate

S23
CAS Number	1010396-29-8
Molar Mass	416.76 g·mol−1
Chemical Formula	C18H13ClF4N2O3
IUPAC Name	(2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide