Description
GW-0742 is a PPARβ/δ agonist that has been shown to improve glucose homeostasis and insulin sensitivity in diabetic rats, as well as increase fat loss by boosting metabolism and stimulating the utilization of fat for fuel. A recent study on diet-induced obese mice treated with GW-0742 and SR9009 (i.e., two times a day for 30 days) has been reported to display decreased fat mass and markedly improved dyslipidemia and hyperglycemia.
GW0742 |
|
CAS Number |
317318-84-6 |
Molar Mass |
471.48g.mol-1 |
Chemical Formula |
C21H17F4NO3S2 |
IUPAC Name |
2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid |
SR9011 |
|
CAS Number |
1379686-29-9 |
Molar Mass |
479.04 g·mol−1 |
Chemical Formula |
C23H31ClN4O3S |
IUPAC Name |
3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide |
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